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Translation of Molecular Genetics in Lung Cancer into Treatment Decision

Article
  1. Christine M. Walko, Pharm.D., discusses how advancements in technology have improved the quality, cost and turnaround time for assessing genetic mutations in tumor tissue, and how this has helped to translate precision medicine into standard clinical practice.
  • Read more about Translation of Molecular Genetics in Lung Cancer into Treatment Decision

Is Targeted Therapy Feasible As Consolidation in Locally Advanced NSCLC?

Video

Dr. Nasser Hanna, Indiana University Health, reviews efforts to utilize targeted therapies as consolidation after chemoradiation in locally advanced NSCLC.

  • Read more about Is Targeted Therapy Feasible As Consolidation in Locally Advanced NSCLC?

Elderly Patients: Selecting Appropriate Systemic Treatment Agents

Video

Dr. Jared Weiss, UNC Lineberger Comprehensive Cancer Center, evaluates a variety of particular systemic treatment agents for possible use in elderly patients.

  • Read more about Elderly Patients: Selecting Appropriate Systemic Treatment Agents

Direct Comparison of 2 EGFR Inhibitors Shows There Are Clinically Significant Differences

Article

Fast forward 1.5 years, and we now have the early results of LUX-Lung-7, and they show that these EGFR TKIs are not completely interchangeable...

  • Read more about Direct Comparison of 2 EGFR Inhibitors Shows There Are Clinically Significant Differences
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Emerging Options for T790M-Positive Acquired Resistance

Video

Acquired resistance in EGFR patients is often driven by the T790M mutation. T790M-positive tumors respond differently to treatments than T790M-negative tumors. Dr. Greg Riely details how each status can predict patients' responses to current treatments.

  • Read more about Emerging Options for T790M-Positive Acquired Resistance

Does the Specific EGFR Mutation (Including "Rare" Mutations) Matter When Choosing an Oral EGFR Inhibitor?

Article

Drs. Leora Horn, Ben Solomon, & Jack West discuss the open question of whether there are clinically significant differences among leading EGFR tyrosine kinases based on the specific EGFR mutation to be treated.

  • Read more about Does the Specific EGFR Mutation (Including "Rare" Mutations) Matter When Choosing an Oral EGFR Inhibitor?

First Line Treatment of EGFR Mutation-Positive NSCLC

Article

MSKCC medical oncologist Dr. Greg Riely reviews the optimal first line treatment of patients with an EGFR mutation-positive advanced lung cancer.

  • Read more about First Line Treatment of EGFR Mutation-Positive NSCLC

Should EGFR TKI Therapy be Continued Beyond Progression?

Article

Dr. Greg Riely, medical oncologist from MSKCC, discusses the controversial question of whether patients should continue on an oral EGFR tyrosine kinase inhibitor after progression.

  • Read more about Should EGFR TKI Therapy be Continued Beyond Progression?

Patterns of Acquired Resistance to EGFR TKIs in EGFR Mutation-Positive NSCLC

Article

Medical oncologist Dr. Greg Riely, MSKCC, summarizes the development of acquired resistance after a good initial response to EGFR inhibitor therapy and the clinical patterns of progression commonly seen.

  • Read more about Patterns of Acquired Resistance to EGFR TKIs in EGFR Mutation-Positive NSCLC

Are There Distinctions Among Currently Available Oral EGFR Inhibitors for EGFR Mutation-Positive NSCLC?

Article

Dr. Greg Riely, medical oncologist from MSKCC, considers the evidence on whether there are clinically significant differences among the currently available first and second generation oral EGFR inhibitors for patients with an EGFR mutation.

  • Read more about Are There Distinctions Among Currently Available Oral EGFR Inhibitors for EGFR Mutation-Positive NSCLC?

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  • EDUCATE
    • Current Patient Education Video Series
      • ASCO Lung Roundtable
      • Bladder Cancer Video Library
      • Cancer Information for the Latino Community
      • Case Based Panel Discussions
      • Clinical Trials Experiences Through Storytelling
      • Coronavirus and Covid 19 in the Cancer Community
      • East Asian Lung Cancer Video Library
      • HPV Advances - A Patient Education Program
      • Head and Neck Cancer News and Updates ASCO / ESMO
      • Lung Cancer Video Library - English
      • Lung Cancer Video Library - Spanish
      • Lung OncTalk
      • Patient Education Ambassador Program
      • Targeted Therapies Patient Forum - English
      • Targeted Therapies Patient Forum - Spanish
      • Testing and Early Diagnosis
    • GRACE Podcasts
    • Video Library
      • English
      • Spanish
      • Mandarin
  • PARTICIPATE
    • Community Forum
      • Bladder Cancer
      • Blood Cancer
      • Brain Cancer
      • Breast Cancer
      • Colorectal Cancer
      • Gall Bladder and Bile Duct Cancer (Cholangiocarcinoma)
      • Head and Neck Cancer
      • Kidney Cancer
      • Lung Cancer
      • Melanoma
      • Member Updates
      • General Forums
      • Ask A Question
    • Get Involved
      • Memorials and Tributes
      • Volunteer Opportunities
  • ABOUT CancerGRACE
    • GRACE NEWS AND INFO
      • Contact Us
      • How (and Why) to Use GRACE
      • GRACE Public Disclosure Documentation
    • About GRACE
      • Mission
      • Opportunities
      • Terms of Use
      • Our Supporters 2020
    • Our Team
      • Faculty
      • Staff and Board
    • Partnerships
      • GRACE and Clinical Care Options Patient Tools
      • Varian Partner Page 2020
      • Takeda Oncology Partnership Page 2020
      • Lilly Oncology Partner Page
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      • More Ways to Give
      • Corporate Giving Programs
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      • Shop and Search for the Cause
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