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Should Immune Checkpoint Inhibitors and Other Therapies Be Combined Concurrently or Sequentially?

Article

Drs. Leora Horn, Ben Solomon, & Jack West consider the merits of administering immune checkpoint inhibitors concurrently with standard first line chemotherapy or targeted therapy vs. sequential treatment.

  • Read more about Should Immune Checkpoint Inhibitors and Other Therapies Be Combined Concurrently or Sequentially?

Are Immune Checkpoint Inhibitors Sufficiently Tolerable to Recommend Them for Older or More Frail Patients?

Article

Drs. Ben Solomon, Leora Horn, & Jack West consider whether immunotherapy might prove to be more problematic when given to a broader population of older and frail patients with advanced lung cancer.

  • Read more about Are Immune Checkpoint Inhibitors Sufficiently Tolerable to Recommend Them for Older or More Frail Patients?

Is It Feasible and Clearly Beneficial to Combine Immunotherapy Approaches?

Article

Drs. Leora Horn, Ben Solomon, & Jack West review the potential rationale and possible limitations of combining different immuntherapy strategies with one another.

  • Read more about Is It Feasible and Clearly Beneficial to Combine Immunotherapy Approaches?

Should PD-L1 be Used as a Biomarker for Immunotherapy in Lung Cancer?

Article

Dr. Eddie Garon, UCLA, reviews the controversial question of whether PD-L1 expression is a reliable enough biomarker to be used to select patients to receive or not receive immune checkpoint inhibitor therapy in lung cancer.

  • Read more about Should PD-L1 be Used as a Biomarker for Immunotherapy in Lung Cancer?

Should PD-L1 Testing Be Ordered at Diagnosis or After Progression?

Article

Drs. Leora Horn, Ben Solomon, & Jack West consider the factors that might lead us to favor testing for PD-L1 at initial workup of a patient with advanced NSCLC or after progression.

  • Read more about Should PD-L1 Testing Be Ordered at Diagnosis or After Progression?

Immunotherapy for Previously Treated Advanced Non-Small Cell Lung Cancer

Article

Immune checkpoint inhibitors are now becoming approved and commercially available for patients with previously treated advanced NSCLC. Dr. Eddie Garon, medical oncologist at UCLA, summarizes key data and explains their current role in treatment.

  • Read more about Immunotherapy for Previously Treated Advanced Non-Small Cell Lung Cancer

Do You Order PD-L1 Testing Before Choosing an Immune Checkpoint Inhibitor?

Article

Drs. Ben Solomon, Leora Horn, & Jack West consider how valuable testing for PD-L1 expression is in clinical practice and whether it should be integrated in clinical decision making around immunotherapies.

  • Read more about Do You Order PD-L1 Testing Before Choosing an Immune Checkpoint Inhibitor?

Clinical Trial Spotlight: Determining Efficacy of Immunotherapy in Stage III Lung Cancer

Article

Dr. Ben Levy discusses two trials that are trying to determine if immunotherapy can help lung cancer patients with earlier stage disease. Click here for information about the PACIFIC trial. The lung cancer vaccine trial will begin in early 2016.

  • Read more about Clinical Trial Spotlight: Determining Efficacy of Immunotherapy in Stage III Lung Cancer

Are there Clinically Significant Differences Among Immune Checkpoint Inhibitors Treating Lung Cancer?

Article

Drs. Leora Horn, Ben Solomon, & Jack West consider whether the data suggest that the better tested PD1 and PD-L1 inhibitors have differences in activity or tolerability or are essentially interchangeable.

  • Read more about Are there Clinically Significant Differences Among Immune Checkpoint Inhibitors Treating Lung Cancer?

Promising Early Results with Immunotherapy for Mesothelioma

Article

Drs. Leora Horn, Ben Solomon, & Jack West review early promising data on the potential activity of immune checkpoint inhibitors in the treatment of malignant pleural mesothelioma.

  • Read more about Promising Early Results with Immunotherapy for Mesothelioma

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    • Find Clinical Trials
    • Glossary
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  • EDUCATE
    • Current Patient Education Video Series
      • ASCO Lung Roundtable
      • Bladder Cancer Video Library
      • Blood Cancer Video Library
      • Cancer Information for the Latino Community
      • Case Based Panel Discussions
      • Clinical Trials Experiences Through Storytelling
      • Covid-19 and Cancer
      • East Asian Lung Cancer Video Library
      • HPV Advances - A Patient Education Program
      • Head and Neck Cancer News and Updates ASCO / ESMO
      • Lung Cancer Video Library - English
      • Lung Cancer Video Library - Spanish
      • Lung OncTalk
      • Melanoma Video Library
      • Patient Education Ambassador Program
      • Targeted Therapies Patient Forum - English
      • Targeted Therapies Patient Forum - Spanish
      • Testing and Early Diagnosis
    • GRACE Podcasts
    • Video Library
      • English
      • Spanish
      • Mandarin
  • PARTICIPATE
    • Community Forum
      • Bladder Cancer
      • Blood Cancer
      • Brain Cancer
      • Breast Cancer
      • Colorectal Cancer
      • Gall Bladder and Bile Duct Cancer (Cholangiocarcinoma)
      • Head and Neck Cancer
      • Kidney Cancer
      • Lung Cancer
      • Melanoma
      • Member Updates
      • General Forums
      • Ask A Question
    • Get Involved
      • Memorials and Tributes
      • Volunteer Opportunities
  • ABOUT CancerGRACE
    • GRACE NEWS AND INFO
      • Contact Us
      • How (and Why) to Use GRACE
      • GRACE Public Disclosure Documentation
    • About GRACE
      • Mission
      • Opportunities
      • Terms of Use
      • Our Supporters 2020
    • Our Team
      • Faculty
      • Staff and Board
    • Partnerships
      • GRACE and Clinical Care Options Patient Tools
      • Varian Partner Page 2020
      • Takeda Oncology Partnership Page 2020
      • Lilly Oncology Partner Page
  • DONATE
    • Why Give to GRACE
      • More Ways to Give
      • Corporate Giving Programs
      • Gifts of Stock or Securities
      • Shop and Search for the Cause
      • Create a Tribute
      • Create Your Own Fundraiser
      • Shop with GRACE