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One of the lung cancer surgeons I work closely with sent me and a couple of the radiation oncologists at my center a report that just came out from a...

A few months ago, I had a patient in my clinic who is a lifelong never-smoker with an adenocarcinoma. I had her tumor checked for molecular markers...

Drs. Bob Doebele, Ross Camidge, and their colleagues at the University of Colorado just published an interesting and clinically relevant paper in...

Thanks (and congratulations) to GRACE member Craig, who highlighted the just-published report that is the first to characterize the frequency and...

Several weeks ago we did a webinar, co-sponsored with LUNGevity Foundation, with Dr. Mark Millard, pulmonologist at Baylor University in Dallas, TX...

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Thank you so much for your
Last Comment by scohn on Oct 9, 2018 1:03 pm
I think that question is
Last Comment by scohn on Oct 9, 2018 1:03 pm
Update on CT Scan
Last Comment by Jim C GRACE Co… on Oct 21, 2018 11:31 am
What is a lateral ventricle transependymal extension of tumor?
Last Comment by scohn on Oct 9, 2018 1:03 pm
What is a lateral ventricle transependymal extension of tumor?
Last Comment by scohn on Oct 9, 2018 1:03 pm

Nexavar (Sorafenib) Shows Survival Benefit for EGFR Mutation-Positive NSCLC but Fails in Broader Population

Article

It has been a long time since we've talked about Nexavar (sorafenib), an oral anti-angiogenic targeted therapy that works as a "multi-kinase inhibitor"  and is FDA approved in some other cancers such as renal cell and liver cancer.  In lung cancer, some small, early research done years ago revealed that it has activity in at least a minority of patients with advanced NSCLC.

Bavitux Redux: If it Looks Too Good to be True, it Probably Is

Article

Just last week I reviewed the favorable results in a randomized phase II clinical trial with the novel vascular-targeting immunotherapy bavituximab, which was associated with an approximate doubling of median overall survival when added to Taxotere (docetaxel) and compared with Taxotere alone, along with a much more modest improvement in response rate and progression-free survival.

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