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I'm just now returning from the International Association for the Study of Lung Cancer's "12th Annual Targeted Therapies in Lung Cancer Conference"...

Many of you already participating on the lung cancer section of the GRACE site have seen the first few responses by Dr. Aggarwal, though they have...

In my thoracic oncology tumor board today, we discussed a situation that comes up fairly often: a patient has a collapsed lung lobe from a tumor near...

One of the very common themes that emerges in the questions from the GRACE community is whether a "local therapy" such as focal radiation or surgery...

The idea is simple enough: we want to identify the patients with a resected early stage NSCLC that has a high risk of recurrence, so that we can give...

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Hi Btlaw, and Janine -
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When might local therapy be a good choice for someone with metastatic lung cancer?

Article

I've mentioned in posts in the past about the settings in which local therapy might be appropriate for someone even when we know the cancer is advanced/metastatic.  Here's a brief video that discusses some of these issues, including a situation in which the local treatment isn't specifically aimed at addressing a symptom, as is the usual reason for treating with local therapy for metastatic cancer, but is rather what I'd consider the "Get the Lead Runner" strategy:

[powerpress]

I'm interested in your thoughts.

More Info on the Correlation of Rash with Outcome on EGFR Inhibitors: My Changing View in Light of the TOPICAL Trial

Article

There's been a theme with the inhibitors of the epidermal growth factor receptor (EGFR) -- both oral tyrosine kinase inhibitors (TKIs) and IV monoclonal antibodies -- that the patients who demonstrate good results with these agents tend to get a rash, while the patients who don't get a rash do poorly.

Why is Chemotherapy a Recommended Part of the Treatment Plan for Most Patients with Lung Cancer, even Early Stage?

Article

Here's a brief video just discussing the rationale for why a systemic treatment like chemotherapy is recommended not only as the cornerstone of treatment for advanced lung cancers, which makes intuitive sense, but also for the majority of patients with earlier stages of lung cancer as well.

[powerpress]

I hope it's helpful.

Webinar on Refining Prognosis of Early Stage Lung Cancer by Molecular Features, with Dr. Johannes Kratz

Article

The next live webinar to be done through the partnership of GRACE and LUNGevity Foundation will be on the timely subject of using molecular features of a resected non-small cell lung cancer in order to better understand the probability of the cancer recurring. This will be on November 14th, 7 PM Eastern/4 PM Pacific, and will hope to answer the question, "Could these molecular features improve upon current staging efforts to help us refine our recommendations of which patients should receive post-operative chemotherapy in order to reduce the chance of recurrence?"

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