In Treatment

Is there anyone else that has this same specific rare cancer gene mutation? This is the first identified mutation for my Non-small cell adenocarcinoma lung cancer.  I would be interested in any treatments or other experiences you are having.  My current treatment is Tagrisso at 80 mg.  After 8 weeks of treatment I had a 60% reduction in the malignant mass in my right lung.  No notable change in pleural lining mass.  Thanks 

Dear Doctors and Moderators!

could you please advise where to go after dramatic progression in bones and lungs on Tagrisso .

first line: carboplatin alimta avastin didn’t work at all

second line: tarceva worked perfectly for 9 months them progressed in lung and bones

third line: Tagrisso without t790m worked perfectly and clear both lungs for 5 months 

now is dramatic progression in bones and lungs .

Tissue biopsy showed my original l858r mutation.