jls57
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Has there been any evidence in pre-clinical data or current clinical trials that indicate AZD 9291 might be effective in treating brain mets or that is effective in. Crossing the blood brain barrier?
Jls57
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Reply # - April 14, 2014, 03:00 PM
Reply To: AZD 9291 and brain mets
I don't believe I've seen any results to speak to this yet. This isn't meant to imply yes or no. I don't think that there have been enough people tested who have known brain metastasis to present an opportunity to determine an answer to the question.
-Dr. West
Reply # - April 14, 2014, 03:08 PM
Reply To: AZD 9291 and brain mets
There doesn't seem to be any evidence at least at this time that this drug crosses the BBB. But is an encouraging drug for those with acquired resistance.
http://www.ascopost.com/ViewNews.aspx?nid=8673
http://cancergrace.org/topic/dr-camidge-on-a-phase-i-study-with-azd9291…