Clinical Trials for my husband - 1264675

betny
Posts:2

My husband has NSCLC, squamous cell. He had a biopsy, and did not test positive for either anti PD L1 and FGFR. He was unable to get into a Clinical Trial that required him to test positve for it, however, he is being put on another one, which did not required him to be either one... Has it proven that it helped patients??? Is there something else out there that would definitely help??

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Reply # - June 29, 2014, 08:07 AM

JimC
Posts: 2753

Hi betny,

Welcome to GRACE. Without knowing which trial your husband is on, we can't say whether it has shown good results yet. Do you know what drug he is receiving? Unless there have been previous trials of the same drug or similar types of drugs, it may be too early to know whether it has been effective.

JimC
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Reply # - June 29, 2014, 10:40 AM

betny
Posts: 2

I do not have the Clinical Trial numbers as of yet. All that I know that its an "Atlantic Trial", that was the rep mentioned, its Astra Zeneca anti PD - L1. I could speak with Moffitt Cancer Center tomorrow and get further information...

I appreciate everything little bit of advice....

Betty

Reply # - June 30, 2014, 09:19 AM

JimC
Posts: 2753

Hi Betty,

Searching the AstraZeneca site (http://www.astrazenecaclinicaltrials.com/ ) for clinical trials of anti PD-L1 agents, it appears that most of their open trials use the drug MEDI4736. It's a bit early for definitive results, but here is a report from a GRACE user with esophageal cancer on his ongoing experience with that drug: http://cancergrace.org/topic/medi4736

JimC
Forum moderator

Reply # - June 30, 2014, 08:27 PM

Dr West
Posts: 4735

All of the immune checkpoint inhibitors are promising, but none of them has been studied well enough to say anythng definitive. MEDI4736 hasn't been as extensively studied as some others, but overall they have all showed relatively similar and encouraging results.

Good luck.

-Dr. West

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