Hi saglia,

Each clinical trial has its own set of inclusion and exclusion criteria. For example, many trials exclude patients who have uncontrolled (untreated) brain metastases. You can examine those criteria in the trial listing at clinicaltrials.gov or contact the trial coordinator for a particular trial.

JimC
Forum moderator

Most systemic therapy trials allow patients to have received gamma knife/cyber knife if a period of something like 2 weeks (perhaps up to 4 weeks) have elapsed since radiation was administered.

-Dr. West