politzer
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Posts:6
After three months off of treatment I've progressed very slightly and will be going back on some sort of treatment. The options at the present time are Afatanib at half-dose or back on Alimta/Avastin or Alimta maintenance. I had a year of first line treatment with Tarceva and progressed and presented T790M mutation. I then went on Clovis and progressed there. Then on to chemo.
So I'm wondering if anyone else has gone from Tarceva to Afatanib and if so, with the T790M mutation. I don't want to assume that the resistance created to Tarceva by T790M isn't applicable with Afatanib.
I'm also curious as to the degree of SE's with Afatanib. I hated Tarceva and couldn't wait to get off but I've heard both sides on Afatanib.
Cheers
Mike
Forums
Reply # - May 6, 2015, 11:47 AM
Hi Mike,
Hi Mike,
I'm sorry you've progressed and must look further. There was an "Acquired Resistance Patient Forum" a few months back that we have videos of. I think you would get a lot out of them. Note that some are specific to ALK mutation that won't apply to you, http://cancergrace.org/lung/acquired-resistance-patient-forum-2014-vide…
Let me know if you've seen them or If you have any new questions after you look them over and I'll ask a doctor to comment.
All best,
Janine