Finishing his 3rd line of chemo July 11 after one year since diagnosis with NSCLC, my husband and I are at the point of considering next steps following assessment of this latest round. He has mostly maintained good vital signs-BP,O-2, HR, stable blood work w/some ups and downs. The exception of the chronic cough for nearly 2 yrs now, hemoptysis, extreme fatigue (perhaps from this round of chemo or just the cumulative effect of cough) and now PleurX catheter + recent weeks' weight loss, both to be evaluated next week.
Knowing from other posts that a 4th line offers limited success, we wonder about exploring other avenues of treatment such as the targeted, precision treatment or a clinical trial. The doctor believes b/c of current fatigue he is not a candidate for trials and has offered a 4th round or palliative care. We are not willing to give up, our faith promises "Nothing is impossible with God," yet want to face what we may be inevitable.
Are there actually successful 4th line chemo or other treatments? From what we read, the %s appear extremely low. From your experience can you offer other direction to explore or other encouragement?
We appreciate any thoughts you have on this.
NSCLC adenocarcinoma 6/18/2012-ULL resected tumor arround pulmonary artery, mediastinal lymph node met; 1st line: chemoradiation ~Carboplatin+Pacitaxel (PET=lung clear >rest for 3 mo); hemoptysis/chronic cough, 1/18/13 neck biopsy skin> adenocarcinoma,1/22/13~w/met indications-(PET/CT) clavical, spine & iliac,2nd line~Taxotere+Zometa; 4/22/13(PET-CT pleural effusion possibly masking ULL malig. activity+other scattered uptake) 5/2/13~3rd 3rd line=chemo~Alimta+Carboplatin , rigid bronch>ablation/cauterization>hemoptysis,cancer in trachea, 6/13/13=PleurX catheter placement, complete 3rd line 7/11/13;