ASCO 2013 Video: Is there a best Avastin-containing regimen for NSCLC? - 1257344

JimC
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The ASCO 2013 video series continues as Drs. Nate Pennell, Mary Pinder and Jack West review the results presented at ASCO 2013 from the POINTBREAK trial of maintenance therapy with the ECOG 4599 regimen vs. carboplatin/Alimta (pemetrexed)/Avastin (bevacizumab) followed by Alimta/Avastin maintenance.

You can view the video here: http://cancergrace.org/lung/2013/06/17/paramount-maintenance-therapy-up…

We welcome your questions and comments here.

JimC
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catdander
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Thanks Jim for posting these links. I think often people don't cross over from the all faculty discussion portion of Grace to the forum and vis versa and some don't even know the other exists so cudos to you and Mark and Denise and Derek for making it happen. 4 years ago July I for one wasn't interested in getting involved with a cancer forum so it took me about a week to realize that the most helpful content on the web came from Grace, that's when I decided to check out the forums...hooked.

I wanted too to speak totally as a consumer of Grace and not a moderator. I was really struck by the conversation in this post. As is so often the case I wasn't expecting to find anything that relates to D's disease but not wanting to miss out on such excellent discussion and knew I should, as a moderator keep up with new content I watched it. D has squamous cell nsclc and isn't a candidate for either alimta or avastin so my personal take home had nothing to do with the drugs in question but I was reminded that options for people with stage IV nsclc are varied and complex.

The most compelling point for me was a warning that even elderly people in outstanding physical condition (an 85 yr old who looks and acts like a 65 yr old) can quickly transition all too quickly into a very frail 85 yr old. This is what happen to my mom she didn't have cancer but she did transition quickly from being a very active 86 yr old (she thought she was being lazy if she went an entire day without being involved in some big project). While I was impressed and hugely proud of my mom and her lifestyle I always worried that she was living in a precariously stable state and the least bit of disruption could knock her off her feet. It did. I'm ok with it, really felt a bit of elation in her passing and how it all went down but of course devastated I'd lost my mom, my emotional protector, the person who loved me and idolized me unconditionally.

I found the post to be a good cautionary tale.