My dad was diagnosed two years ago with NSCLC adenocarcinoma stage IV. He had radiation of bone and brain metastases and completed two six-round cycles of combined carboplatin and alimta/abraxane. He had a severe allergic reaction to carboplatin in December 2012, so is now just receiving alimta. He also had a recent third biopsy to determine genetic mutations; results showed that he has ERBB3 amplification, actionable with pertuzumab, and PTCH1-P155S, actionable with vismodegib. As these medications are not yet approved for lung cancer, we wondered what to do now.
Sun, 03/31/2013 - 18:32#1
Biopsy with genetic mutations completed but still unsure what to do now.. - 1255299