Hi everyone. I'm looking for anyone who has a BRCA2 mutation and advanced NSCLC. Husband is now taking PARP Inhibitor Lynparza b/c last year one of his second line treatments - Avastin - supposedly caused his colon to perforate and his onc doesn't want to put him back on traditional chemo/immunotherapy. The Lynparza seems to be working - enlarged lymph nodes have gotten smaller. Challenge is that Medicare won't cover it since it's off label for LC. We had to pay an enormous sum out of pocket before we qualified from assistance from the manufacturer and are appealing this denial at the fourth level (hearing with a judge) Any and every bit of research on the effectiveness of this drug with LC is welcome and any info on incidence of this mutation with LC is also. I recently listened to a webinar by American Ling Association and submitted a question regarding incidence but the oncologist who took the question just said it's not often found. Thanks!