My mum's oncologist decided that the next line of the treatment for my mum will be carboplatin monotherapy. The reason for carboplatin alone and not in combination with paclitaxel are low neutrophils (1.59) and low white blood cell count (3.59). Does anyone know anything about the efficacy of carboplatin alone? I am really afraid as we had really rapid progression on single agent pemetrexed in 2nd line. Also reports say that chemotherapy with just a single agent is the worst option after first line afatinib. Time on monotherapy treatment reported in retrospective analysis of LUX-Lung trials was just 2.3 months (which means almost immediate progression). My mums treatments so far are described here: https://www.inspire.com/daxys/ Thanks in advance!
Thu, 09/13/2018 - 09:13#1
Carboplatin alone (monotherapy) ?