I have started Tagrisso on Mar. 8 2018, 80mg for 64 days and 40mg for 365 days,
After these days my PET/CT scan has shown progression of 10mm GGO at LLL, color-fading away of one GGO at LLL and another GGO at RLL, on May 24 2018.
On the other hand gene mutation analysis had shown mutation T790M and L858R, at a surgery three years ago.
The 10mm GGO at LLL is in the deeper place of lobe.
My onc. said radio frequency ablation is possible.
Can I expect Tarceva?
What is the next choice?
2003 (photograph a very low contrast image (not diagnosed) X-ray LUL S3)
2004 DX a GGO LUL S3
Feb 17 2005 progression to three GGOs RUL RLL
Feb 23 2005 partial resection a 1cm BAC RUL S3
lobectomy a 3.3cm AD mixed BAC LUL S3
Jan 25 2008 progression max 1 cm multi focal GGOs RLL S8 S9
development primary max 1 cm multi focal GGOs LLL S9
Feb 8 2008 partial resection two max 1 cm multi focal GGOs RLL S8 S9
Apr 25 2008 progression multi focal GGOs RLL
May 2 2008 progression LLL
development primary GGO RLL S9
May 11 2008 a round of Carboplatin Paclitaxel
Jul 11 2008 start Tarceva
Sep 26 2008 stable RL
stable or shrinkage LL
Nov 18 2008 NED
Dec 2012 development new GGO LLL
Jan 19 2015 progression an 8mm primary GGO LLL
Apr 20 2015 development a 4mm primary GGO RLL
May 7 2015 progression to two GGOs (8mm) LLL
progression to two GGOs (4mm) RLL
Jun 8 2015 stop taking Tarceva
Jun 26 2015 partial resection a tumor (11mm) RLL S6 EX20 T790M+ EX21 L858R+
watch and wait a GGO LLL
Sep 28 29, Oct 1 2 2015 SBRT 48gray X ray a GGO (12mm) RLL S6
Dec 4 2015 Radio Frequency Ablation a GGO (16mm) LLL
Jan 5 2016 lung capacity 3.55L predicted vital capacity 3.27L
Mar 8 2016 progression to multi focal GGOs RLL watch and wait
Jun 7 2016 progression to two GGOs LLL
Sep 27 2016 progression to multi focal GGOs (13mm 5mm