Question: Does anyone know of emerging research or clinical trials being done with ARID1A mutation for lung cancer here in US?
History: I am stage IV lung cancer (non small cell lung cancer) with brain metastases. I was diagnosed August 2015 stage 3 (right lung)---non-smoker, age 49 at diagnosis; treated with cistoplatin/etoposide 2 cycles and and 33 concurrent radiation treatments to lung and mediastinum.. NED in lung since December 2015. Two (2) episodes (June 2017 and March 2018) of brain mets in occipital lobe both treated with surgery and subsequent Cyberknife.
I have pulmonary fibrosis secondary to Sjogrens syndrome. Thus, I am unable to to benefit from use of immunotherapy. My molecular testing results were positive for: ARID1A, KMT2C, NKX2-1, NOTCH2, XRCC2.
I have conducted searches and conducted a few researchers. But there doesn't seem to much on the horizon for ARID1A in relation to lung cancer. Did anythong come out of recent (2018) ASCO meeting?
P.S. This is my first time posting. Hope I did it correctly.