My mother has Stage III lung cancer. She's gone through chemo and radiation and now is on Opdivo (since late November). She seems to be tolerating it fine however she had a lesion/tumor on her chest that has gotten worse since then. And so her doctor did a scan on it (in December) and decided it was likely cancer (didn't do a biopsy) and decided to radiate it. It's still hurting (she just finished radiation last week on it.) She's also discovered another lump on her arm, near where the Opdivo was administered.
The doctor did however think that her lungs had improved quite quickly from Opdivo already, that there has been a response and it was early on for that to be happening. Could this new lump/increased one potentially be a pseudo progression? Could it be a weird infection or allergy? Or maybe Opdivo is only partially working?