My mother, 68yrs, no history of smoking or second hand smoke, diagnosed with NSCLC. 50% of tumor is sarcomatoid and 50% is adenocarsinoma. The original biopsy did not have enough material to do mutation testing. She has already had 20 radiation treatments and was told that tumor could not be re-biopsied. The doctor said the only way to get new biopsy was through surgery to remove tissue from one of the two new small tumors just recently found in her lung. The only other tumors found were in her brain. There were 2 very small tumors that have been radiated and are presumed gone.
My mom starts general chemo, carboplatin/taxol, next Thursday.
We are weighing the pros and cons of surgery to biopsy the new tumor for mutations. Her doctor is not sure if it will matter given her type of cancer. What are the pros and cons of doing the surgery? Can it make a difference in her prognosis? Should we consider the surgery/biopsy?