I'm on tarceva and I received biopsy results on some progression today. However, I was told that there is more testing going on because my nsclc might have mutated to a neuroendocrine sclc tumor. The oncologist said this is extremely rare and that the odds are with me that it is still nsclc with a different method of resistance. I am hoping that this is the case as he feels he can treat the resistance with radiation and keep me on the tarceva. I won't know however until Monday.
Do you know what percentage of tarceva resistance is due to a mutation to sclc? When it does mutate to sclc, does it tend to mutate to a neurendocrine tumor? I've seen statistics somewhere with the sclc data, but of course cannot find them now that I need them.