I've been on Crizotinib for 21 cycles and have done very well with virtually no side effects. My stage 4 ALK+ NSCLC initially shrunk and has been stable ever since per my CT scans. During this time, I experienced three fungal infections. The last one was treated with Fluconizol which required me to stop Crizotinib for 21 days due to the drug interaction.
There doesn't seems to be any information available about stopping Crizotinib without progression. I'm interested in understanding the risks of not taking Crizotinib while progression free. Can one go back on Crizotinib and expect it to work or maybe take it at a lower dosage?