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Can we improve on XALKORI? New agents for patients with an ALK-1 rearrangement
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Dr. Mary Pinder reviews promising studies from ASCO 2013 on second gen. ALK inhibitors LDK-378, CH5424802, and AP26113 in patients with ALK-positive advanced NSCLC, including impressive activity in crizotinib-refractory patients and those with brain mets.

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acquired resistance
ALK Rearrangement
ALK-positive
anaplastic lymphoma kinase
AP-26113
AP26113
ASCO 2013
CH-5424802
CH5424802
Chugai
Cleveland Clinic
crizotinib
crizotinib-refractory
Howard Jack West
Howard West
Jack West
LDK 378
LDK378
Mary Pinder
Mary Pinder-Schenck
Moffitt Cancer Center
Nate Pennell
Nathan Pennell
Swedish Cancer Institute
XALKORI

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