Selective Androgen Receptor Modulator GTx-024: A New Effective Treatment for Cancer Cachexia?


Anorexia-cachexia syndrome (ACS), a negative spiral of diminished appetite and weight loss (lean body mass), is a common problem in many kinds of cancer, where it not only leads to patient weakness and diminished function but is also associated with shorter survival.  While it’s possible that the ACS is a late effect that might be an irreversible product of progression of an underlying cancer, it may also be that ACS directly contributes to a patient’s decl

More Challenges with EGFR Rashes


Rashes from EGFR inhibitors: we like to see them, because we know that many trials have shown that skin toxicity on drugs like tarceva is associated with better survival (see prior post), but the fact is that sometimes a rash is more than an inconvenience and can really make people miserable, or at least pretty unhappy, as described in the comments and questions from a discussion forum thread today.

Acupuncture: Introduction and Use for Pain Control


Acupuncture is a complementary approach that originated from traditional Chinese medicine, from a theory that the flow of vital energy, or "Qi" (pronounced CHEE, I believe, unless someone who speaks Chinese tells me otherwise) can be regulated by stimulation of key body areas with needles, heat, or pressure. It is generally felt to be quite safe when performed by properly qualified individuals, although caution is appropriate for patients with a tendency toward increased bleeding or known low platelets.

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