My mum is in treatment for Stage 4 Adenocarcinoma and recently had her ALK genetic mutation testing results which state - 'no ALK gene rearrangement, but additional copies of ALK gene locus detected'. Her oncologist explained that this means she is Negative for ALK gene mutation but could not explain what 'additional copies of ALK gene locus' means.
What does 'additional copies of ALK gene locus' mean?
Could you explain if this has any effect on her possible genetic mutation status?
We would like to be sure that we fully understand the implications of her ALK testing before we proceed to testing for the more rear genetic mutations such as ROS1.