My dad has stage 4 lung cancer, mets to the brain and bones - he was diagnosed in mid August, and so far has only received gamma knife surgery for his brain mets. He is Egfr negative, although a chemo-sensitivity test confusingly suggests tarceva would be effective against his cancer. Nivolumab also suggested positive results. A third treatment option would be traditional chemo (carboplatin/pemetrexed).
I have been trying to build up his weight and immune system - since nivo essentially utilities the bodies own immune system, it seems to make sense it should precede chemotherapy, as chemo would whilst hopefully working against the cancer, would also work against the immune system. Does this make sense or am I missing something?
He has lost quite a lot of weight recently, 62kg/6 feet tall, my fear is chemo may exacerbate his weight loss, so I'd be keen for nivolumab to precede chemotherapy. Any suggestions as to the best treatment order would be greatly received.