Large Cell Neuroendocrine Carcinoma of the Cervix? - 1242130

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Large Cell Neuroendocrine Carcinoma of the Cervix? - 1242130


My 25-year old, married daughter was diagnosed with squamous cell cervical cancer with pelvic lymph node involvement on Valentine's Day of this year.

The following week she underwent a radical hysterectomy and pathology results revealed the 4.5 x 2.5cm cervical tumor was actually metastistic large cell neuroendocrine. One malignant pelvic lymph node was also removed during the surgery.

Yesterday she finished three consecutive days of carbo and etoposide. In two weeks she will undergo six weeks of external radiation with once weekly cisplatin. That will be followed with another three days of carbo and etoposide.

We have been told this cancer is very rare, extremely resistant to treatment, and incredibly difficult to cure.

1. Does anyone else have experience with this specific type of disease?

2. If so, is the treatment protocol we are undergoing similar to yours?

3. What results have you seen with your treatment?

Thanks so much for your help. We are just beginning what seems to be a very long journey.

Dr West
Reply To: Large Cell Neuroendocrine Carcinoma of the Cervix?

I'm sorry to say that we are really specialists on our particular cancers, but gynecologic cancers aren't among them. We hope to bring in experts in more cancers over the next several months and years, but right now we don't have the particular expertise you're looking for.

-Dr. West

Dr. Howard (Jack) West
Associate Clinical Professor
Medical Oncology
City of Hope Cancer Center
Duarte, CA

Founder & President
Global Resource for Advancing
Cancer Education

With regard to the article

With regard to the article highlighting it as a story about someone with cancer and not “lung cancer” specifically, I don’t think that one source needs to be perceived as a slight. His particular piece was more about the struggle of having a parent dying of a terminal disease, or cancer more specifically, than discussing the details of managing his cancer. I think it can be taken as a more universal experience of people facing a progressing cancer (of any type) than a story specific to lung cancer. And Dax Shepherd himself didn’t shy away from describing it accurately.