My wife had been taking a break from chemo (Alimta/pemetrexed) for the past three months due to her 10/2/2012 CT scan showing significant response in the primary left lung tumor as well as “dramatic” decrease in the size of the nodules throughout both lungs. In addition, there was extensive regression in both osseous metastasis and lymph glands. While she tolerated the 14 sessions of pemetrexed quite well, she did experience hair thinning, skin discoloration and a good deal of fatigue. Her last chemo session was 10/17/2012 and since then hair, skin and energy levels are almost back to normal. Having said all that, she had another CT scan last Monday 1/7/2013 that showed continued regression of lung nodules/lesions with “no mediastinal or hilar adenopathy, no pericardial effusion and no osteolytic lesions visualized”. However, the loculated pleural fluid in both the upper left lung and the lower right lung remain unchanged (5-6mm) from the 10/2/2012 CT scan. We were thinking that taking a break from pemetrexed might help these dissipate and hopefully over time they will. She has an appointment with her Oncologist next Wednesday and I guess we will make the decision to continue the pemetrexed break or start back on the chemo at that time. She will probably be lobbying to go another three months without chemo but it is hard to know the right thing to do with this sinister disease. It is worth noting that her first line (and only line) of treatment was with pemetrexed and not a doublet including a platinum based drug. Good news overall I think.
Fri, 01/11/2013 - 13:10#1
Update On Wife’s Condition - 1252494