Article and Video CATEGORIES

Cancer Journey

Search By

Dr. Jack West is a medical oncologist and thoracic oncology specialist, and Executive Director of Employer Services at the City of Hope Comprehensive Cancer Center in Duarte, CA.

Screening Trial for Never-Smokers
Sun, 01/18/2009 - 16:13
Howard (Jack) West, MD, Associate Clinical Professor, Medical Oncology, Executive Director, Employer Services, Founder, President and CEO of GRACE

One of the principles of screening is that the likelihood of detecting a cancer depends greatly on the risk that a person being screen has for developing that cancer. Low risk means that it is very likely that any abnormality that is detected is more likely to be unrelated to cancer. And because of that, nearly all of the screening efforts thus far have focused on patients with a significant smoking history.

But there are some patients who have a higher risk, even despite an absence of a smoking history. Among those would be considered at higher risk without a smoking history would be people with a significant family history of lung cancer (particularly an increased risk among people with a family history of lung cnacer in never-smokers, though the risk is still quite low), and people with a significant history of exposure to secondhand smoke. And now there's a study being done by a group that has a particular interest in the risk of lung cancer from secondhand smoke: flight attendants.

The Flight Attendants Medical Research Institute has sponsored a screening study for never-smokers (less than 100 cigarettes in a lifetime), a minimum age of 40 (cancer risk is age-related), significant exposore to secondhand smoke, no cancer history, and no prior CT in the preceding three years. The trial is currently being conducted at New York Presbyterian Hospital/Cornell's Weill Medical School in New York, Swedish Cancer Institute in Seattle, and some others. You can learn more about the trial here.

Next Previous link

Previous PostNext Post

Related Content

Forum Discussions

Hi JGromo, Welcome to Grace. I'm so sorry your dad and by extension, you are going through this. If it helps, I know how you feel. My husband is going through...

I agree that not all docs are good communicators! Remember they are people just like us, filling a very important role. I echo Janine's comment to ask questions here -- our...

While no one can give advice or recommend treatments on a forum our faculty can be invaluable when talking about current thought and practices.


This is the response via email...

From Dr. West, He reminds us, "The principle is not to over-react to minimal change." and suggests this article and the ones on oligoprogression linked in the above post.  "Note in...

Hi Sean,

Welcome to Grace. I'm so sorry you're going through this. I can only imagine your worry about metastases and I hope that's not the case.
Liver hemangiomas are thought...

n3p, Hi and welcome to Grace. I'm sorry you have to check for new nodules. It does sound like your onc has good reason not to be alarmed that you have...

Thanks for the thoughtful response, I really appreciate that! All your points make sense. I will check back in later.

Recent Comments

From Dr. West, He reminds us…
By JanineT Forum … on Tue, 02/07/2023 - 19:49
This is the response via…
By JanineT Forum … on Tue, 02/07/2023 - 19:02
I agree that not all docs…
By JanineT Forum … on Tue, 02/07/2023 - 18:21
Hi JGromo, Welcome to Grace…
By JanineT Forum … on Mon, 02/06/2023 - 14:44