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Dr. Jack West is a medical oncologist and thoracic oncology specialist who is the Founder and previously served as President & CEO, currently a member of the Board of Directors of the Global Resource for Advancing Cancer Education (GRACE)

 

Is there a new, promising option for people with the most common mutation seen in lung cancer?
Author
Howard (Jack) West, MD

The report of the phase II randomized trial of MEK inhibitor selumetinib for KRAS mutation-positive NSCLC was just published in Lancet Oncology.  Here's my discussion of some of the highlights of this work and what this means.

[powerpress]

I'm hoping we'll have more information to update everyone on the developments in the story of MEK inhibitors for KRAS mutation-positive NSCLC, and perhaps also a broader population of patients with NSCLC, in the next year or two.

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Hi elysianfields and welcome to Grace.  I'm sorry to hear about your father's progression. 

 

Unfortunately, lepto remains a difficult area to treat.  Recently FDA approved the combo Lazertinib and Amivantamab...

Hello Janine, thank you for your reply.

Do you happen to know whether it's common practice or if it's worth taking lazertinib without amivantamab? From all the articles I've come across...

Hi elysianfields,

 

That's not a question we can answer. It depends on the individual's health. I've linked the study comparing intravenous vs. IV infusions of the doublet lazertinib and amivantamab...

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