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Dr. Jack West is a medical oncologist and thoracic oncology specialist who is the Founder and previously served as President & CEO, currently a member of the Board of Directors of the Global Resource for Advancing Cancer Education (GRACE)

 

Round Table Case-Based Discussion -- Drs. Laskin and Sandler on Molecular Testing in a Never-Smoker
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Howard (Jack) West, MD

Here is the first podcast of what we plan will be an ongoing series of round table discussions with cancer experts about real case scenarios and how we make decisions in practice. My guests for the discussion are Drs. Janessa Laskin, medical oncologist from British Columbia Cancer Agency in Vancouver, BC, and Alan Sandler, medical oncologist and Director of Hematology/Oncology at Oregon Health & Science University in Portland.

The first case we discussed is a relatively young Asian never-smoking woman with an advanced lung adenocarcinoma, focusing first on the changing standards for sending tissue for molecular testing, as well as the limitations of that. Here is the video version, audio, transcript, and associated figures.

[powerpress]

round-table-laskin-sandler-never-smoker-mutn-testing-audio-podcast

round-table-laskin-sandler-never-smoker-mutn-testing-transcript

round-table-laskin-sandler-never-smoker-mutn-testing-figures

The case continues with the next podcast, discussing first-line chemotherapy-based treatment options and maintenance therapy. Look for that next week.

I've completed several initial podcasts with colleagues from around the country just over the last few weeks, using largely my own cases. However, as I mentioned in an earlier post, we are happy to consider your own cases and questions if you would like to submit them and have questions that are timely and potentially relevant to a broad audience in the cancer community. So if you're interested, please e-mail a brief synopsis and perhaps your central question(s) to west@cancergrace.org for consideration.

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Hi elysianfields and welcome to Grace.  I'm sorry to hear about your father's progression. 

 

Unfortunately, lepto remains a difficult area to treat.  Recently FDA approved the combo Lazertinib and Amivantamab...

Hello Janine, thank you for your reply.

Do you happen to know whether it's common practice or if it's worth taking lazertinib without amivantamab? From all the articles I've come across...

Hi elysianfields,

 

That's not a question we can answer. It depends on the individual's health. I've linked the study comparing intravenous vs. IV infusions of the doublet lazertinib and amivantamab...

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